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Vikram University, India
Title: Supramolecular aspect of advanced membrane technology

Uma Sharma received M.Sc. Physical Chemistry in1981, M.Phil. in1982 and Ph.D. In 1985 under the guidance of ( Prof. V.W. Bhagwat ,Alexander von Humboldt Fellow) from Vikram University,Ujjain India. In 1989 she received Indian Science Congress Young Scientist Award, INSA visiting Fellowship and in 2006 Indo Hungarian Fellowship. She received Dr D.S.Bhakuni Award (2013) by Indian Chemical Society,Kolkata. A major focus of her research is Supramolecular Chemistry - Design and synthesis of podands and redox switched ionophores/receptors and their use in facillitated transport of biologically important metal ions/ amino acids/ carbohydrates through Liquid Membrane Systems. Biocompatibility of fullerenes and drug encapsulation in chitosan based nanoparticles are the other field of her interest.She is fellow of Indian Membrane Society and Indian Science Congress Association,Kolkata.She delivered more than 20 invited talks on Membrane Science and Supramolecular Chemistry. Synthesis of molecular containers i.e.Cucurbiturils, Rotaxanes and Dendrimers for specific purpose as sensors and molecular devices are her future projects .


In 1987, D J Cram, J M Lehn and C J Pedersen were awarded Nobel Prize in Chemistry “for their development and use of molecules with structure specific interactions of high selectivity” and coined the term Supramolecular Chemistry. Jean Marie Lehn further linked supramolecular chemistry to adaptive chemistry due to lability/reversibility of noncovalent interactions which enable constitutional variations and the transition from design to selection through exchange, uptake and release of the molecular components of supramolecular entity. Supramolecular chemistry has been invaluable in elucidating some of the principles underlying the structure and function of the membranes. Molecular recognition is the biochemical basis of supramolecular chemistry and results in selective binding. The separation and selection of species from chemical or biological molecular pool is dependent upon its selective interaction with molecular receptors. Design and synthesis of molecular receptors/ionophores/enzymes/synthetic transporters for specific purpose is the revolutionary concept in advanced day membrane technology. When chemical reactions are coupled with membrane permeation many interesting phenomena can occur. If reactions are carried out inside the membrane,the membrane acts as more than a partition and these membranes are called reactive membranes with increased flux - a revolution in unit operation and reactive membrane engineering. Liquid Membrane systems transport various substrates as cations/anions/amino acids/neutral species/drugs from one phase to another facilitated by designed ionophores/receptors. Reactive membranes can be prepared by loading a selected membrane support with specially designed selective carriers/enzymes/membrane mimetic agents/natural and synthetic receptors. Reactivity control in membrane separation has been expected exponential growth in analytical, environmental and biomedical applications.

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Membrane Science 2017
Membrane Science 2017
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